The museum at Hokkaido University comes from the acquisition of the Botanical Garden Museum, which was managed and operated by pioneers in 1884 (Meiji 17) during the Sapporo Agricultural School era. The Botanical Garden Museum is currently under the jurisdiction of the Hokkaido University Northern Biosphere Field Science Center, and is a separate organization from the General Museum.

Examination of the installation of the general museum on the Sapporo campus was started in 1966 (Showa 41), and the installation was admitted from the Ministry of Education in 1999 (Heisei 11) after the idea that spans about 30 years.

The General Museum aims to integrate and manage in good condition the academic specimens produced as research results for 140 years since the opening of Sapporo Agricultural School, and to disseminate information inside and outside the university.

The general museum as an internal organization is the main building (northern 10 Article West 8 chome) on the Sapporo Campus campus, Sapporo No. 2 Farm (north 18 Article West 8 chome), and the Fisheries Science Museum (Hakodate City Port Town) Hakodate Campus It consists of 3 facilities.